Melanoma and vitamin D  

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Brian
Eminent Member
Joined: 3 years  ago
Posts: 20
18/11/2016 12:51 pm  

We have had conversations regarding our Vit-D levels on the survivors page and a lot of us have had tests and a mojority of the tests came back low. This is a report from the Journal of clinical oncology regarding this matter

"Should every newly diagnosed patient with melanoma have a serum vitamin D level determined? This is a more difficult question to answer, and certainly no definitive statement can yet be made, although evidence to support this approach seems to be mounting. Although one might think that the high sun exposure and fair skin coloration of the typical patient with melanoma would mean that most patients would have normal vitamin D levels at diagnosis, a significant number of patients with melanoma in the cohorts studied were serologically vitamin D deficient; as noted above, sun exposure alone does not guarantee vitamin D sufficiency.5,7,8 Moreover, a meta-analysis of studies that looked at serum vitamin D levels and the incidence of cutaneous malignancy found no association between vitamin D level and risk of melanoma development, although there was a clear association with nonmelanoma skin cancer risk.12 Guidelines for routine screening for vitamin D deficiency are still very much in flux,13 and the cost effectiveness of routine screening of vitamin D levels at diagnosis in patients with melanoma has not yet been addressed. That notwithstanding, the apparently large number of patients with melanoma who have low or deficient vitamin D levels at diagnosis combined with the routine recommendation for patients to avoid unprotected sun exposure after diagnosis and treatment, along with the real possibility that patients with lower vitamin D levels may fare worse than those with higher levels, seems to provide strong rationale for routine determination of the 25-hydroxyvitamin D level at initial diagnosis followed by oral supplementation and additional monitoring for patients with low or deficient levels.

You can read more by following this link

Journal of clinical oncology


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